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Showing posts from April, 2023

Electrophoresis Power Supply: A Comprehensive Guide

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An electrophoresis power supply is an apparatus that powers and controls the electrophoresis experiment and generates a requisite amount of electric field to allow the separation of molecules in an electric field. It has a wide range of applications in the separation as well as analysis of biomolecules like plasmids, proteins, nucleic acids, DNA and RNA. What are The Applications of Electrophoresis? The process of electrophoresis is used in various research and laboratory centers and is widely used in the area of DNA and RNA fragmentations. Here are a few of its applications - DNA Analysis and Fragmentation : The most important application of electrophoresis is the evaluation of DNA fragments . DNA has a negative charge consistency and it gets affected by the presence of an electrical current. A test material like an agarose gel is used for the separation of a specific DNA strand. Used in Protein detection : The is commonly used in detecting the existence of the protein in chemical...

What to Know About Gene Synthesis?

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Gene synthesis is a well-known process among researchers that enables them to specify a desired sequence and custom-build the gene directly. Gene synthesis is a straightforward, faster, and cost-effective process than other alternative methods of molecular cloning and mutagenesis. This process involves multiple steps that include cloning strategy design, primer synthesis, PCR, gel extraction, bacteria transformation, and other complex steps, gene synthesis can give you a faster and more accurate outcome. Here are the steps of gene synthesis process in brief - Oligonucleotide synthesis Amplification: PCR Fragment Assembly Fragment Sequencing Correcting Errors: Fragments Vector Insertion Selecting Clones Sequencing Gene: First Round Correcting Errors: Gene Sequencing Gene: Final Round Key Advantages of Gene Synthesis This process can be used for a short period of synthesis cycle and 100% correct sequence. It delivers excellent flexibility in modifying restriction sites and gene sequence...

A Comprehensive Guide On CRO-CMO Industry

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CRO is a short form of Contract Research Organisation that provides affordable clinical research support to various biotech, medical and pharmaceutical industries on a contract basis. The CRO-CMO industry has grown a lot in the past few years to outsource research services and they are quite popular due to their cost-effective solutions for companies seeking to develop new medicines for both large and niche markets. What are the typical services provided by CRO-CMO? Contract Research Organisations provide a comprehensive range of services that includes the following: Biopharmaceutical developments: Oligo Synthesis, Peptide synthesis, Gene Synthesis, DNA sequencing, antibiotic and protein synthesis and antibody production. Molecular biology kits productions Electrophoresis and PCR-related services. Preclinical and clinical trials. Quality and metric reporting. Data entry validation. Full project management. What are the benefits of hiring CRO-CMO services? There are many benefits of co...